LOS ANGELES -- On a night when the Seattle Mariners and Los Angeles Dodgers traded blows like a heavyweight bout, it was a relatively unheralded outfielder who delivered the knockout punch. Dominic Canzone, a left-handed hitter with a quiet swing, turned the game upside down with his second home run of the night, a two-run shot in the eighth inning that gave Seattle a 7-6 win in the series opener at Dodger Stadium.

The dramatic swing came off Dodgers reliever Alex Vesia, who had entered the game with a one-run lead. After Julio Rodriguez singled and swiped second base, Canzone worked the count in his favor before sending a high fly ball to deep center field. The ball carried 414 feet, just clearing the wall and landing in the grass beyond the outfield fence. The Mariners dugout erupted as Canzone circled the bases, his second homer of the game and the fifth for Seattle on the night.

Earlier, the Dodgers had shown their characteristic resilience, erasing deficits and pushing back each time the Mariners scored. They had taken a 5-4 lead in the fifth on Max Muncy's solo shot, and another rally in the seventh gave them a 6-5 edge. But the bullpen, which had been a strength all season, faltered at the worst moment.

Seattle's offense had been relentless from the start. Cal Raleigh went deep in the first inning, and Rodriguez followed with a solo blast in the third. Rob Refsnyder, activated from the injured list just before the game, crushed a two-run homer in the fourth to put the Mariners ahead 4-2. Canzone then tied the game at 5 in the sixth with a 433-foot bomb that seemed to deflate the home crowd.

For the Dodgers, Shohei Ohtani provided the early fireworks, leading off the bottom of the first with an opposite-field, two-strike homer that traveled 434 feet, just one foot farther than Canzone's first. Muncy's solo shot in the fifth was a no-doubter, giving Los Angeles a short-lived lead. But the Dodgers' inability to hold any of their three one-run leads proved costly.

Dodgers starter Justin Wrobleski, who had allowed only eight homers in 107 innings this season, was surprisingly vulnerable. He surrendered four home runs over six innings, a stark departure from his usual command. Mariners starter Luis Castillo was equally hittable, allowing five runs on 11 hits in five innings, but his bullpen bailed him out.

The ninth inning brought drama. Dodgers closer Andres Munoz, who had been nearly automatic, allowed a leadoff single to Dalton Rushing. Shohei Ohtani then ripped a double to right field. Victor Robles, inserted as a defensive replacement, misjudged the ball on the warning track, and it squirted out of his glove, allowing Rushing to score and Ohtani to reach third. After a walk to Max Muncy, Mookie Betts stepped to the plate with two outs. Betts grounded sharply to second base, but the Mariners turned the final out, sealing the victory.

Jose A. Ferrer got the win with a scoreless eighth inning, improving to 4-1. Brock Stewart took the loss for the Dodgers, falling to 0-1. The Mariners improved to 48-42, while the Dodgers dropped to 55-35 but still hold a comfortable lead in the NL West.

Both teams are expected to continue their series on Wednesday, with Seattle sending right-hander Emerson Hancock (6-4, 3.16 ERA) to the mound against Los Angeles lefty Eric Lauer (5-5, 4.83). The game will be pivotal for the Mariners, who are trying to climb back into playoff contention, while the Dodgers aim to rebound from a rare home defeat.